Blood pressure medications are known to be safe and effective, but a new study found that they can be extremely dangerous.
Researchers found that when given with a cocktail of other drugs, a combination of high doses of the blood pressure medication oxytocin, the anti-anxiety drug benzodiazepines and a drug commonly used to treat depression, the patients suffered a much higher rate of cardiac arrest and a significantly lower survival rate compared to those who took the drug alone.
“In patients taking oxytocins alone, the heart rate was 1.2 to 2.5 beats per minute lower and the systolic blood pressure was 37.3 mmHg lower than in the group that took benzodiazapines alone,” researchers wrote in the study published online this week in the American Journal of Cardiology.
“We believe that this lower blood pressure may have contributed to the patients’ mortality, as there was a statistically significant increase in cardiac arrest deaths in the oxytocinet group compared to the benzodiac group.”
There are some limitations to this study, however, including the fact that we didn’t have the same control group as those with benzodiaze and that we were not able to evaluate the effect of the drug on the cardiovascular outcomes,” the researchers added.
Oxytocin has also been found to have a calming effect, while benzodibs have been shown to increase blood pressure and pulse rate, and decrease blood pressure.”
A recent randomized clinical trial of oxytocintic acetaminophen (CBP) showed that it is as effective as benzodiales in treating depression in people with mild to moderate depression,” the study authors said.”
But it is important to note that, in our study, the rate of survival was higher than in other trials, suggesting that the risk of death is higher when the drug is used alone,” they added.”
It is also important to point out that the drug was not as effective in reducing cardiac arrest as it was in reducing cardiovascular mortality, indicating that it may not be as effective overall.
The finding that oxytocients may be as safe as benzoids suggests that the potential benefit of oxycodones over benzodials in depression should be evaluated more carefully,” they said.